“But what lifts Determined above the level of most science documentaries is the storytelling.
THE INTIMACY IS POWERFUL, as if the families have invited us into their homes.”
– Catherine Caparello, Isthmus





The Story
Three women at high risk for Alzheimer’s disease offer their brains and bodies to a medical study. After losing their mothers to the disease, these daughters are determined to contribute to the search for a cure. Meanwhile, they anxiously watch for signs of the disease in their own brains.
This independent documentary, filmed over five years, intimately shows what happens when human test subjects – who are at high risk for developing Alzheimer’s disease – offer their blood, brains, and hearts to conquer it.
Since Dr. Mark Sager took the initiative in 2001, medical research scientists at the Wisconsin Alzheimer’s Institute have been on a mission – to figure out how to prevent, and eventually cure, Alzheimer’s disease.
Their method is to track the characteristics and habits of people at high risk for the disease, and to observe them in biological detail as they age. Some convert to Alzheimer’s disease and some do not. Why?
After humble beginnings, the study—the Wisconsin Registry for Alzheimer’s Prevention (WRAP) —is now recognized by the National Institutes of Health as a high-priority research site.
At the heart of the Alzheimer’s study are the test group participants – middle-aged adults with a deceased or living parent with Alzheimer’s disease. Parental history makes the test group 2.5x more likely to get the disease than those without a history of it in their families.
The human research subjects are followed by the scientists for a minimum of 15 to 20 years and undergo periodic and rigorous cognitive tests.
The test group also shares one of life’s most difficult trials – a parent’s decline from Alzheimer’s disease.
This is a story about the fight to stop Alzheimer’s disease as told by the people with the most on the line.

The Characters




Barb, Karen and Sigrid also return every two to three years to undergo the signature experience – a multidisciplinary oral cognitive test. This battery of questions looks for problems with their memory that signal their worst fear—the onset of Alzheimer’s disease.
By combining clinical, brain imaging, biomarker information and physical fitness data, scientists are in pursuit of both the causes of the disease and what lifestyle practices may help delay the onset. It’s a race against time, but thus far, Alzheimer’s has been the victor.
As the researchers compile data from 1,500 participants over the first period of the study, a narrative begins to emerge.
How soon will an answer be found?
Can it be found in time?
Film News
DETERMINED Part of the Green Bay Film Festival
We are proud to announce DETERMINED (www.gbfilmfestival.org/determined) has been selected to be part of the Green Bay Film Festival. DETERMINED will be available to watch on your favorite device from February 1 to April 4th. Information on tickets is available...
The Isthmus Reviews DETERMINED
DETERMINED is a feature story this week in The Isthmus (Wisconsin's alt-weekly newspaper). Reporter Catherine Capellaro goes in-depth about the film's origins, the filmmakers, the research subjects featured in the film, and the storyline.
We Have a First Trailer!
We are pleased to announce that DETERMINED will have its official world premiere at DOCUTAH the first week of November! It's an in-person festival, with masks and spacing, in some amazing theaters. We are deeply grateful to every one of the people in our film, to the...
Filmmakers

Therese Barry-Tanner
PRODUCER/SOUND
Therese Barry-Tanner has been a participant in the WRAP study for more than fifteen years. Therese understands Alzheimer’s disease at an intimate level. She assisted her father in caring for her mother with the disease. Later she advocated for her mother fiercely at a nursing home —her mother was unable to speak for herself. Therese lost her mother to Alzheimer’s disease in November of 2008. DETERMINED began as Therese’s idea in 2011. Therese hopes that DETERMINED will bring the audience through the emotional journey and difficult decisions that are made when a loved one lives with or dies from Alzheimer’s disease. She also hopes the film will share the experience of being a human research subject, and that it will offer an inside look at the people who are working to find a cure. Prior to producing, Therese worked in healthcare, with over 30 years in program and project management, most recently specializing in healthcare reform and physician quality assurance at a Fortune 500 company.

Melissa Godoy
DIRECTOR/CINEMATOGRAPHER/EDITOR

Eileen Littig
PRODUCER
Eileen Littig is an independent producer and former Director of NE Wisconsin In-School Telecommunications. With Wisconsin Public Television, she produced social issues programming and has been recognized with two Midwest Emmys – both for stories about teenage girls: Beyond the Butterfly and The Discovery of Dawn. She produced numerous creative and important programs for youth, including Sexual Orientation: Between the Labels. which earned a Gold Medal from the CPB. Littig was Co-Producer for the documentary Do Not Go Gently, narrated by Walter Cronkite. The film received a Gold World Medal in Humanities from the New York Film and Video Festivals and a National Media Award from the American Society on Aging. Littig serves on the Wisconsin Educational Communications Board and is a community activist.

Shawndra Jones
SOUND RECORDIST/KEY GRIP

Amy Kruep
SOUND/GRIP

Jo Hillman
ASSOCIATE PRODUCER
Jo became a WRAP human test subject in 2002, while caring for her mother during advanced stages of Alzheimer’s disease. She is also active in the National Institutes of Health All of Us Research Project, working to accelerate health research and medical breakthroughs and enabling individualized prevention, treatment, and care. Jo actively incorporates scientific findings into nutrition, exercise, and sleep protocols in an effort to mitigate the potential onset of age-induced decline. She is a certified trainer for A Time to Heal, a cancer survivorship program having facilitated group sessions since 2014. She is also an ImaginAging facilitator for the AgingUp Network. Previously, Jo had a long career in higher education as a teacher, senior level manager and consultant for national and international colleges and universities.

Karen Y. Durgans
Impact Producer
Karen was Associate Producer and Outreach Coordinator for Steven Bognar and Julia Reichert’s A Lion in the House, an Emmy Award-winning documentary and national outreach project (Independent Lens/PBS). Durgans was a field researcher for the U.S. Financial Diaries Project, a research and development partnership between New York University Wagner’s Financial Access Initiative and the Center for Financial Services Innovation. She provided research, logistical and audio support for “American International Health Alliance: Partners in Health,” which profiled international sister-city partnerships in Armavir, Armenia and Galveston, Texas. “Partners in Health” aired in Season 10 of the award-winning PBS series, The Visionaries. Karen cared for both her stepfather and mother during her family’s journey with dementia.

Jean Wentz
Production Assistant
Partners
Center for Independent
Documentary
The Center for Independent Documentary (CID) collaborates with independent filmmakers to create documentaries on issues of contemporary social and cultural concern. CID is the fiscal sponsor of DETERMINED and manages the project funds through their 501(c)(3). They bring expertise in fundraising, production, and distribution. Recent CID projects include the Netflix-Higher Ground Productions acquisition Crip Camp by Jim LeBrecht & Nicole Newnham, Dawnland by Adam Mazo & Ben Pender-Cudlip, Nancy Kates’ Regarding Susan Sontag (HBO), and Cheryl Furjanic’s Back on Board: Greg Louganis. Founded in 1981, CID’s programs have screened at major festivals, aired nationally and locally on public and cable television, and earned numerous awards.
Alzheimer’s Association
GREATER WISCONSIN CHAPTER
The Greater Wisconsin Chapter aided in securing initial funding for DETERMINED, which was instrumental to making the project a reality. It is one of over 70 Alzheimer’s Association chapters across the United States and shares the organization’s mission: “To eliminate Alzheimer’s disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health.”
Major funding for this film was provided by:
And many additional donations from generous individuals, including those honoring a loved one who died of Alzheimer’s disease. |
Take Action
Help us finish the film DETERMINED.
Contact
For questions or media inquiries, please email us at will.i.b.next@gmail.com.